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SURPASS-2: the landmark trial SURPASS-2 enrolled 1,879 adults with type 2 diabetes who had inadequate blood sugar control on metformin alone, at doses of 1,500 mg or higher per day

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PAXLOVID includes ritonavir, a strong CYP3A inhibitor, which may lead to greater exposure of certain concomitant medications, resulting in potentially severe, life-threatening, or fatal events
