does tirzepatide cause blood clots Can Clots? Staying Safe Does Tirzepatide Cause Blood Clots?
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10.4093/dmj.2023.0277 4 ChenW.CaiP.ZouW.FuZ

Yes and this is physiologically normal
Nadler says

Kidney Function Problems Reports of acute kidney injury have surfaced, often tied to dehydration from vomiting or diarrhea

The lower cost of these meds might influence insurance coverage, too