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Therefore, these observations suggest something other than maternal food intake in the GLP-1R activation-induced fetal growth restriction during late pregnancy

Graham, U

New molecular entities (NMEs), as defined by the FDA, are new drug products containing as their active ingredient a chemical substance marketed for the first time in the United States

However, their pharmacological effects alter eating behaviour, gastrointestinal dynamics and weight loss patterns in ways that may indirectly influence nutritional status

As of April 2026, tirzepatide is FDA-approved only as a weekly injection (Mounjaro for type 2 diabetes, Zepbound for weight management)