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The studys main findings were that compared to placebo: Semaglutide lowered the relative risk of a non-fatal heart attack by 26% It also lowered the relative risk of a stroke by 39% And lowered the relative risk of a major cardiovascular event by 26% This sounds significant

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Mice were acclimated in metabolic treadmills to obtain baseline oxygen consumption measurements followed by 30 min of pre-running (10 m/min) before initiating the VO 2 max protocol (Figure 5A)