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Conclusion Adults with T2D initiating semaglutide OW in the real-world had significant decreases in weight, BMI, and HbA1c after 1 year, with greater improvements versus SGLT2i, and similar HCRU.

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GLP-1 receptor agonist use appeared linked to significantly reduced all-cause mortality among people with sickle cell disease, according to study results presented at ASH Annual Meeting and Exposition.People who used the medications also exhibited reduced risk for other adverse outcomes, including sickle cell crisis, venous thromboembolism, ischemic stroke or transient ischemic

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