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That nerves modulate inflammation in the intestine is well established, but the anti-inflammatory effects of vagal nerve stimulation have only recently been discovered, and positive effects of this approach were seen in only some patients with Crohns disease in a single trial

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Because of the high unit price and total expense of these medications, countries are now deliberating on whether and how to cover them as treatments for obesity [64]

This pattern likely reflects differences in baseline fitness: individuals who regularly perform longer workouts are generally more fit and therefore exhibit lower resting heart rate and higher HRV[2]

Mice were double- or single-housed and unless otherwise indicated fed ad libitum with either a regular chow (1314, Altromin or 5L0D, LabDiet) or HFD (58% fat, D12331, Research Diets) under constant ambient conditions of 22 2 C with constant humidity (4565%) and a 12 h:12 h light:dark cycle