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Understanding Anthem and GLP-1 medications GLP-1 receptor agonists have transformed the weight loss landscape

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GLP-1RAs may also have effects on a transcriptional level via protein kinase A (PKA), phosphorylating cAMP-response element-binding protein (CREB) in the nuclear membrane to enhance preproinsulin transcription [28]

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[DOI] [PMC free article] [PubMed] [Google Scholar] 104.Douros A, Filion KB, Yin H, et al