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The pathway for compounded GLP-1s has not closed entirely: legitimate patient-specific 503A compounding, with individualized clinical documentation, at the four-prescription safe harbor ceiling, remains legally available for genuine edge cases such as documented allergies to branded product excipients

Always disclose existing medications and conditions to ensure safe compounding and dosing personalization

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Additionally, patients with diabetic retinopathy should have regular eye monitoring, especially when initiating treatment or increasing the dose