retatrutide gip glp-1 glucagon receptor agonist PDB-101: Molecule of the Month: Agonists retatrutide triple agonist glp-1 gip
Description
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Aims/hypothesis Insulitis, a hallmark of inflammation preceding autoimmune type 1 diabetes, leads to the eventual loss of functional beta cells

Phase 3 development is ongoing under Eli Lilly's TRIUMPH program

Eli Lilly reported another success in a study pitting its once-daily oral GLP-1 therapy Orforglipron against a competing type 2 DM therapy, this time AstraZeneca's SGLT2I Farxiga (Dapagliflozin)
Protect muscle, control hunger, improve results, and support long-term weight loss.