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This study not only found that the cGAS-STING-ferroptosis pathway was a druggable target in joints, but also pioneered a new flexible delivery platform that resolved the key limitation of low local drug concentrations in joints after systemic administration, and offered a cartilage-protecting perspective for RA

Their decision is binding

These effects result from the medication's mechanism of slowing gastric emptying

A single 24-hour delay will not eliminate the drug's appetite-suppressing or blood-sugar-control effects

*Correspondence: Jens Juul Holst [email protected] This article was submitted to Molecular and Structural Endocrinology, a section of the journal Frontiers in Endocrinology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers