tirzepatide osa approval FDA's First GLP-1 for Sleep Apnea May Reduce Reliance on CPAP Zepbound (Tirzepatide, GLP1RA), is the
Description
2025 doi: 10.1093/ehjcvp/pvae093
Assessment of Effect on CVS A total of 3,297 patients with T2D and high risk of CVD were randomised in 104-week double-blind trial to receive either semaglutide 0.5 mg/1 mg once weekly or placebo 0.5 mg/1 mg as an add-on to the conventional therapy of CVD for the next two years

Individual experiences with GLP-1s may vary , and further research is still needed to fully understand the long-term effects of GLP-1 medications and their potential applications in various mental health conditions

However, the study included a small number of participants and a shorter follow up time of only 48 weeks compared to other RCTs studying GLP-1 agonists

Other reported side effects include injection site reactions (pain, redness, swelling), low potassium levels (hypokalemia), and potential heart failure when combined with thiazolidinediones