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When should I stop gliclazide (sulfonylurea) in a patient with controlled blood glucose levels on Ozempic (semaglutide), linagliptin (DPP-4 inhibitor), and metformin (biguanide)?

However, a systematic review in 2023 found only one phase 2 randomized controlled trial of exenatide versus placebo for IIH, which did demonstrate a significant reduction in ICP at all time points, as well as improved headache and visual acuity (7,8)

doi: 10.1016/j.molmet.2020.101102 [DOI] [PMC free article] [PubMed] [Google Scholar] 34.Davidson MB, Bate G, Kirkpatrick P

The launch of oral GLP-1s coupled with lower prices and broader access (including Medicare and Medicaid coverage in the U.S.) should drive higher utilization and market penetration as more affordable and convenient options become available, Schott said

Although these events are uncommon, clinicians must evaluate individual risk factors before initiating therapy
