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More importantly, semaglutide and tirzepatide are not interchangeable on a milligram-for-milligram basis

Thus, in the context of pharmacotherapeutic use of modern GLP-1 RAs and in terms of understanding the cardiovascular effects of such treatment, the biology of the truncated GLP-1 metabolites can be disregarded (Cherney et al., 2021)

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Several changes could contribute to lower pricing before generic versions are widely available: Manufacturer price reductions

Hogan AE, Gaoatswe G, Lynch L, Corrigan MA, Woods C, O'Connell J, et al
