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Consistent with this, chronic GLP-1R agonism has been demonstrated in several mouse models of AD to prevent the development of memory deficits [[834], [835], [836]]

[4] [5] Such development typically takes many years and must meet rigorous regulatory standards set by the MHRA and European Medicines Agency (EMA) before any product could be approved for patient use

Another study published in the Journal of Clinical Endocrinology & Metabolism found that a GLP-1 agonist was effective in reducing body weight and BMI in obese women with PCOS who were also being treated with metformin, a medication commonly used to treat insulin resistance

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