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The primary objective was to determine whether dapagliflozin 10 mg reduces the incidence of the composite endpoint of 50% sustained decline in eGFR, progression to end-stage kidney disease (ESKD) (defined as sustained eGFR 40% and evidence of structural heart disease to determine whether dapagliflozin reduces the risk of cardiovascular death, hospitalization for heart failure or urgent heart failure visits

During clinical trials, participants experienced an average weight loss of 12.4%

That's why these drugs are so effective when it comes to managing type 2 diabetes and weight gain

The rapid transit bypasses the normal gastric reservoir function, creating a 'nutrient bolus' effect that triggers excessive incretin secretion