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Improving How Long Patients Live The ENZAMET trialfunded in part by the drugs manufacturer, Astellas Pharma, as well as government health agencies in Canada and Australiaenrolled more than 1,100 men (largely outside of the United States) with hormone-sensitive metastatic prostate cancer
In a meta-analysis including seven CVOTs and approximately 56 thousand participants, the use of GLP1RAs in patients with type 2 diabetes reduced the risk of total stroke by 16% (HR = 0.84
Collectively, these three pathways suggest that GLP-1 RAs may exert direct effects on BP regulation independent of weight loss
Women of pregnancy potential should practice effective contraception while on semaglutide therapy and the drug should be discontinued at least 2 months before a planned pregnancy
Importantly, individuals who stopped taking GLP-1 receptor agonists regained 10% of their lost weight within a year (13)
