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The upward trend in the rate was observed among 50-59-year-olds and 60-69-year-olds, and the trend among 20-49-year-olds remained relatively constant from 2017 to 2021 and then rapidly increased from 2021 to 2022 (Appendix 3)

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Both estimands were used for the primary treatment period analysis for primary and secondary endpoints, unless specified otherwise

doi:10.2337/diabetes.51.3.652 22