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Obesity-induced and weight-loss-induced physiological factors affecting weight regain

They are not signals to stop the medication

Ignoring Hydration Dehydration slows weight loss, worsens side effects, and in severe cases can lead to kidney complications

[1] Understanding the established side effect profile is important when considering whether new or unexpected symptoms may be related to Wegovy treatment

At week 88, patients receiving tirzepatide lost an additional 6.7% of their mean body weight from randomization, while patients receiving placebo gained 14.8% of their mean body weight, for a placebo-adjusted net weight change of -21.4%