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Overall prescribing rates (GLP-1 RA prescriptions per total prescriptions) in December 2025 increased slightly relative to September 2025 (+5.0%) and now account for more than 7% of all prescriptions

Specifically, the insulin glargine/lixisenatide FRC product can provide a maximum of 60 units per injection of basal insulin, and the insulin degludec/liraglutide product can deliver a maximum of 50 units per injection of basal insulin

Obesity Canada is leading that charge, she said

It is crucial to note that in most CVOTs the primary endpoint was a composite endpoint of major adverse cardiovascular events (MACE), with HF hospitalisation typically a prespecified secondary or exploratory outcome

Co-prescribing Rybelsus and Januvia is generally not recommended in clinical practice