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2019;4(12) doi: 10.1172/jci.insight.124819
However, Retatrutide is superior in that it also targets glucagon receptor (GCGR) and gastric inhibitory polypeptide receptor (GIPR) in addition to encouraging insulin exertion with GLP-1 receptors
Approval expected 2027-2028 after NDA submission Phase 2 vs Phase 3: Phase 2 (Jastreboff et al., NEJM 2023) showed 24.2% weight loss at 48 weeks
[DOI] [PubMed] [Google Scholar] 127.Liu C, Li C, Cai X, Zou Y, Mo J, Chen B, et al
