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Diarrhea is a common side effect reflecting your body's adjustment to GLP-1 activation, but it is not a requirement for weight loss

She wrote in her book that she took them for 20 years, and recalled suffering from body image issues that were so severe she would sometimes hear voices in her head telling her, 'Do more sit-ups, fat a**.' Oprah When Oprah Winfrey stepped onto the red carpet at the Louis Vuitton Cruise Show in Italy earlier this week, she showcased an incredibly slimmed down physique Throughout her decades-long career, the now 69-year-old TV legend (seen left in 1988, center in 1992, and right in 2008) has been extremely open about her weight loss journey When Oprah Winfrey stepped onto the red carpet at the Louis Vuitton Cruise Show in Italy earlier this week, she showcased an incredibly slimmed down physique

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