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The biased GIP signaling is often cited as a reason for its improved GI profile compared to pure GLP-1 agonists
Semaglutide can also lower blood sugar levels, so close monitoring is extremely necessary for individuals who have diabetes or those taking other medications that lower blood sugar

Report any vision changes promptly and ensure your GP, diabetes specialist, and optometrist are aware of all your medications

Studies document approximately 10% tolerance to phentermine effects within the 3 to 6 month window, which is why prescriptions are limited to 12 weeks in most cases
