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162,168 Whereas ratios of tumor to pancreas (9.71 at 48 h) and other organs were high, a low ratio of the tumor to kidney (1.27 at 48 h) was observed

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A randomized controlled study that followed 44 normoglycemic children and adolescents with obesity from early puberty to puberty completion demonstrated that, although Metformin improved anthropometric parameters such as BMI z-score, waist circumference and percent body fat, it did not have a beneficial effect on insulin sensitivity or -cell function compared to placebo (193)

[DOI] [PMC free article] [PubMed] [Google Scholar] 27.Dhillon S

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