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These side effects typically occur when you first start taking the medication or after a dose increase

A boxed warning is the strongest safety-related warning issued by the FDA

Some of the most meaningful transformations show modest scale changes but dramatic improvements in body shape, health markers, and quality of life

The state of play in 2026 For years, clinicians compared tirzepatide and semaglutide across separate trials with different patient populations, different endpoints, and different study designs

It can cause fatigue, along with shakiness, sweating, confusion, dizziness, blurred vision, or a rapid heartbeat