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GLP-1 receptor agonists are recommended as either first-line or second-line therapy regardless of baseline hemoglobin A1c in patients who have established atherosclerotic cardiovascular disease, high risk of atherosclerotic cardiovascular disease, chronic kidney disease, or heart failure

doi: 10.1016/j.mce.2013.01.009

in the New England Journal of Medicine , June 2023 [5][2]

The average effective dose ranges from 1.0-2.4mg weekly, with higher doses associated with greater weight loss but increased side effects
