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Scientists have now created long-lasting GLP-1 drugs that can be used to treat type 2 diabetes, obesity, and a range of other conditions

Understanding the difference between appetite-suppressing drug classes helps patients and providers choose the most appropriate treatment based on individual physiology, comorbidities, and clinical response patterns

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As presented at the American Diabetes Association Meeting: this randomized phase 2b trial in 230 adults with overweight or obesity shows that aleniglipron, an oral small-molecule GLP1-RA, led to up to 11.3% body-weight loss compared with placebo after 36 weeks of treatment.