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Afshin A, Forouzanfar MH, Reitsma MB, Sur P, Estep K, Lee A, et al

Headaches emerge as one of the most frequently reported side effects during the first weeks of semaglutide treatment, affecting approximately 1 in 4 patients according to clinical trial data
In several animal species, for example, the drug exenatide has been able to help reduce cocaine self-administration, decrease the frequency of relapse-like behavior, and reduce dopamine release after cocaine is consumed

Ingesting alcohol or taking other drugs along with diphenhydramine can intensify the experience of being high, but its extremely dangerous

Maintenance is optional
