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Gastric emptying is already slowed by the drug

Three-fourths of HR decision-makers are aware of GLP-1 medications and acknowledge them as beneficial for controlling blood sugar, boosting weight loss, improving blood pressure and lowering the risk of heart disease among others

Despite these findings, to our knowledge, there are no large population-based studies that have investigated the incidence of new-onset major cardiovascular events or clinically significant portal hypertension events in patients with MASLD who are receiving treatment with GLP-1 agonists for any indication

Outside of the positive benefits that these medications have on weight loss they also have many other benefits

In conclusion, GLP-1RA is a promising candidate drug therapy for pediatric MASLD, and patients may benefit from metabolic improvement even if the liver disease ameliorating effects are not yet clear