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Medical management of hyperglycemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy: a consensus statement of the American Diabetes Association and European Association for the Study of Diabetes
Another limitation of the studies was the use of different comparators ranging from placebo controls to other medications for T2DM (including insulin), which have different effects on bone tissue and were included in only one group, misleading the interpretation
A meta-analysis of four trials with 158 participants demonstrated significant reductions in body weight, fasting plasma glucose, and insulin resistance [16]
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Overall, the elimination half-life is approximately 13 h, making it a suitable preparation for once-daily injection
