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Nevertheless, cAMP signaling in response to exendin-4 was enhanced in -arrestin-less cells, as evidenced by the increased potency relative to wild-type, as well as a tendency to increased efficacy over time (Supplementary Fig
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This dual approach may lead to more effective appetite suppression and improved glucose metabolism compared to Ozempic, which targets only the GLP-1 receptor

doi: 10.1016/j.febslet.2014.03.051

50 mM l-valine (cat
