can semaglutide cause vomiting and diarrhea Why Causes Diarrhea: Understanding GLP-1 Effects on Gut Motility & Digestion Ozempic side effects | Ozempic
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Phase 2 Trial Results (NEJM 2023) The landmark Phase 2 trial enrolled 338 adults with obesity (BMI 30) or overweight with comorbidities (BMI 27) but without diabetes

However, for those with mild to moderate kidney impairment, empagliflozin can still be used, albeit with caution and under close monitoring

research funding from GlaxoSmithKline, Takeda, Bristol-Myers Squibb, and Novo Nordisk
GLP-1 medications typically cause weight loss, which may not be appropriate if you are already underweight or nutritionally compromised Gastrointestinal complications : Do you have strictures, fistulas, or a history of bowel obstruction
Some common GLP-1 side effects can also make hydration more difficult