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Beyond being able to go pound-for-pound with semaglutide, tirzepatide may also have superior effects on certain metabolic biomarkers, since its both a GLP and GIP agonist

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For context, the Mounjaro FDA prescribing information lists injection-site reactions among the documented adverse events across the SURPASS trials at roughly 3-7% uncommon but consistent enough that a methodical approach matters from day one