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[DOI] [PMC free article] [PubMed] [Google Scholar] 79.Long-Term Intervention with Pravastatin in Ischaemic Disease (LIPID) Study Group, Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels

Doctors want to check how well it works for many types of patients and get the right facts for FDA approval

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Gastrointestinal events may be more noticeable during escalation periods in some incretin-based studies, depending on the structure of the trial
Incidence Rates and Clinical Trial Data on GLP-1Associated Headaches Major clinical trials for semaglutide, tirzepatide, and other GLP-1 agonists document headache occurrence across different patient populations, doses, and indications
