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Development of thermogenic adipocytes within WAT, sometimes called beiging or browning, has been observed in humans with conditions accompanied by heightened adrenergic stress such as chronic cold exposure or burn trauma [3,15,16]

[30], it was observed that patients with type 2 diabetes had a decreased rolling velocity and increased adhesion of polymorphonuclear leukocytes (PMNs) to the human umbilical vein endothelial cell (HUVEC) monolayer