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To stay ahead of this shifting environment, pharma companies should consider the following imperatives: Massive patient drop-off undermines obesity GLP-1 uptake: Despite strong demand, only 10% of obesity patients persist with therapy after one year

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Considering the central role of glucose catabolism for stimulus-secretion coupling in -cells, our findings suggest that chronic GLP-1 actions on insulin secretion include elevated -cell glucose metabolism

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GLP-1 benefits can help lower blood sugar, reduce body weight, and lower the risk of heart attack
