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GIP is a separate gut hormone that plays a role in insulin secretion, fat metabolism, and energy balance

Hyponatraemia (low sodium levels) is a recognised risk with SSRIs including sertraline, particularly in older adults or those taking diuretics

[16] [19] Some research suggests these anti-inflammatory effects may occur alongside weight loss, though the relative contributions of direct immunomodulation versus metabolic improvement remain unclear

GLP-1 is released eating and lasts only about 1-2 minutes before an enzyme called DPP-4 breaks it down

Stopping GLP-1 therapy tends to bring appetite back, often leading to weight regain