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GLP-1s are becoming a bigger part of weight management

Recent developments underscore the relevance of GLP-1R agonists in addressing the complex interplay of cardiovascular-kidney-metabolic (CKM) syndrome, microvascular dysfunction, and metabolic-associated steatohepatitis (MASH)

These fibres are fermented by beneficial bacteria into short-chain fatty acids such as butyrate and propionate, which activate receptors on intestinal L-cells responsible for GLP-1 secretion

Development of a ligand-based proximity labeling strategy enables interrogation of the native cell membrane interactome for the GLP-1 receptor in two cell types, revealing new regulators of receptor-mediated signaling and cell responses.

In under-resourced parts of Los Angeles, people develop life-altering, preventable diabetes complications related to obesity