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Importantly, several phytochemicals demonstrate metabolic benefits by enhancing GLP-1/GIP signaling through DPP-IV inhibition, providing a biologically plausible route for synergistic neuroprotection in PD (Malar et al., 2020

The terminal half-life of MEDI4166 in cynomolgus monkeys based on Fc and GLP-1R activity in the 100 mg/kg (sc) group were determined to 147 and 116 h respectively (Supplementary Table 4)

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[20] [21] La evaluacin de la eficacia glucmica debe realizarse peridicamente, considerando ajustes teraputicos cuando no se alcanzan los objetivos individualizados

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