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Rationale and design of a multicenter placebo-controlled double-blind randomized trial to evaluate the effect of empagliflozin on endothelial function: the EMBLEM trial

An important drug discovery challenge

GLP-1 drugs mimic incretin hormones that signal satiety and delay gastric emptying

Liraglutide Treatment Reduces Endothelial Endoplasmic Reticulum Stress and Insulin Resistance in Patients with Diabetes Mellitus

Large cohort studies and meta-analyses show no substantial long-term increase in thyroid cancer risk with GLP-1 RA use
