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Persistent nausea can create a general sense of malaise that patients describe as fatigue, while the physical effects of frequent vomiting or diarrhea can cause legitimate exhaustion

Endocrine (2015) 48(1):10715

Major challenges confronting the future of GLP-1 receptor agonists is their cost and accessibility

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Even modest reductions in micronutrient availability may therefore influence catalytic velocity across interconnected metabolic pathways, potentially amplifying bioenergetic and redox constraints under chronic flux limitation [112, 113]
