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GLP-1 receptors are present in brain regions involved in reward processing, including the nucleus accumbens and ventral tegmental area

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Change in BMI (%) Wegovy pen delivers significant, sustained BMI reduction at week 68 3,4 Supportive secondary end point 4 14.7% (~36 lb) mean weight reduction with Wegovy vs 2.7% (~6 lb) mean weight increase with placebo at 68 weeks Mean baseline body weight: Wegovy =242.3 lb
Available at: Accessed August 30, 2019
