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Prescribing information for approved GLP-1 medications does not list colorectal cancer as a known adverse effect, though the FDA requires ongoing post-marketing surveillance for all novel therapeutic agents

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Liraglutide alleviates H2O2-induced retinal ganglion cells injury by inhibiting autophagy through mitochondrial pathways

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The current KDIGO guidelines do not recommend SGLT2i for people in more advanced stages of CKD (eGFR 300 mg/g) and reduced progression of UACR in people with macroalbuminuria when compared with placebo

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These results are similar to those of Azzam et al., 17 who found that GLP-1 RAs contributed to a 72% decrease in blindness or visual abnormalities at 3 months with long-lasting advantages at 24 months

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Optum Rx can provide precision analytics to demonstrate cost impacts spanning multiple scenarios as well as expert clinical consultation and insights to help you make timely decisions

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