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Notwithstanding, previous studies have documented beneficial effects of the activation of estrogen receptors in diet-induced obese females, by reducing body weight and fat accumulation and improving leptin resistance at central level 53,54
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Meta-analyses show berberine producing 2-3 pound weight loss over 12 weeks in best-case scenarios 30 Ye, Y
JAMA Intern Med 177(5):633640
