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Because it provides a constant level of insulin regardless of blood sugar status, blood glucose can drop dangerously low if a patient skips meals, exercises vigorously, or takes too much insulin

Both classes of drugs improve glycemic control in T2DM patients but only the GLP-1R agonists given at pharmacological doses will cause weight loss

They do not act against a single addictive substance, they act against the craving that drives addictions

It's a constellation of symptoms that we see from, not only the rapid weight loss, which is what we're learning, but also some specific changes that we're seeing in the skin that are likely a consequence of the medication, Henry said

These findings led to a suggested role for GIP in the development of obesity, highlighting the therapeutic opportunity of GIP receptor antagonism, and subsequently leading to great interest and research activity within the field (53)