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[DOI] [Google Scholar] 5.Gastaldelli A., Cusi K

The study found that weight regain was relatively minimal, whether subjects lost weight from injectable semaglutide (Wegovy) or tirzepatide

Patients may need a more careful discussion if they have a history of: Previous NAION in one eye Significant optic nerve crowding Diabetes with vascular complications Sleep apnea, especially untreated sleep apnea High blood pressure or low nighttime blood pressure Cardiovascular disease Sudden unexplained vision loss in the past This does not automatically mean a GLP-1 medication is unsafe, but it does mean the patient should have a personalized risk-benefit discussion with their medical provider

It impacts around 18% of people with diabetes and exhibits a higher prevalence than in those without diabetes
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