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In our PCOS models, GLP1/E may ameliorate hypothalamic inflammation, as reflected by a reduced expression of proteins related to the immune system, and attenuate apoptotic responses
Comp Biochem Physiol B Biochem Mol Biol 121(1):4956 Mentlein R, Gallwitz B, Schmidt WE (1993) Dipeptidyl-peptidase IV hydrolyses gastric inhibitory polypeptide, glucagon-like peptide- 1(736)amide, peptide histidine methionine and is responsible for their degradation in human serum
Pathological processes such as oligodendroglial insulin signaling defects, glial inflammation, mitochondrial stress, and impaired proteostasis overlap with pathways modulated by GLP-1R stimulation
What are you seeing among patients using GLP-1 weight loss medications
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