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There are no symptoms for high cholesterol, but some health conditions that can lead to unhealthy cholesterol levels include:9 Chronic kidney disease Diabetes HIV/AIDS Hypothyroidism Lupus Cholesterol can also be elevated by certain medications for conditions such as:9 Acne Cancer High blood pressure HIV/AIDS Irregular heart rhythm Organ transplants High cholesterol can cause plaques to accumulate on the walls of your arteries, which can lead to chest pain, heart attack, or stroke

GLP-1R has been densely found in the choroid plexus, suggesting the possibility it may play a role in sodium transport and cerebrospinal fluid (CSF) production [102]

Dulaglutide decreased the hyperphosphorylation of tau and NFs proteins through improving the PI3K/Akt/GSK3 signaling pathway, which may be related to its protective effects on impaired of AD-like learning and memory (150)

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Yuen et al