glp-1 agonist drugs Receptor Agonists and Other GLP-1 Receptor Agonist Shortage: Challenges
Description
The proportion of patients who achieved the HbA1c goal ranged from 25.9% (95% CI 18.534.9) with alpha -glucosidase inhibitors to 63.2% (54.171.5) with the long-acting GLP-1 analogue
doi: 10.1056/NEJMoa2403347 [DOI] [PubMed] [Google Scholar] 257
As previously mentioned, GLP-1RAs inhibit the mTOR signaling pathway, which in turn alleviates the inhibitory effect on the cell cycle regulatory protein p27 [17]
Liraglutide isnt found in nature but is artificially synthesized by a process called recombinant DNA technology from yeast cells
Lancet Diabetes Endocrinol 2022;10:193206.ArticlePubMed 50
