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Mice treated with MOTS-c showed dramatic resistance to diet-induced obesity even without changes in caloric intake

Continue this stepwise escalation by 2.5 mg every 4 weeks as tolerated, with goal of reaching 10 mg or 15 mg depending on response and tolerability

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The balancing of potential confounding variables was evaluated using standardised mean differences (SMD) with a threshold set a priori at 0.10

To learn more about GLP-1 agonists, including their benefits and potential side effects, feel free to read on