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Ligumsky H., Wolf I., Israeli S., et al., The PeptideHormone GlucagonLike Peptide1 Activates cAMP and Inhibits Growth of Breast Cancer Cells, Breast Cancer Research and Treatment 132 (2012): 449461

In that study, exendin-4 not only ameliorated albuminuria but conferred kidney structural benefits including reduced glomerular hypertrophy and mesangial matrix expansion in the absence of an effect on body weight, blood pressure, or circulating glucose concentrations

As clinicians gain more experience with these medications, lower-dose strategies are proving to be more sustainable for both results and adherence

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Approval is not guaranteed, and the specific credentials of your assigned provider (MD, NP, PA) may vary